Be sure to cut a groove in the weld zone of a thicker piece. Then “landslide” the side walls of the host metal into the bottom of the trough you created. Fill to the top with similar filler metal.
You can do most welding with 30-gauge fill material. If you need a larger piece of weld material, shoot the end of the 30 gauge wire to make it ball up to a larger diameter piece, then weld.
Think of laser welding settings like water coming from a garden hose. Turning on the water (whether all the way or partially) is the voltage. The nozzle is the beam diameter. How long you hold the water in one place is the equivalent of the millisecond setting.
A good rule of thumb for changing laser settings to enhance performance is to increase/decrease the milliseconds (duration of the beam) first, and then the beam size, and the voltage last.